[Intestinal cryptococcosis: an unusual presentation of disseminated cryptococcosis]. / Cryptococcose digestive: une présentation inhabituelle de cryptococcose disséminée.

Cryptococcosis is a serious infection caused by an encapsulated yeast-like fungus, Cryptococcus neoformans. It is pathogenic most often in the lungs and central nervous system of immunocompromised patients. In this work we report an unusual localization of cryptococcosis in an HIV-infected patient. This rare localization was diagnosed from a stool sample sent to our laboratory for parasitological study. Direct examination of fresh stool showed the presence of many large, rounded thick-walled fungi. India ink staining of the stool showed encapsulated cryptococci, and C. neoformans was isolated by culture. Despite flucanazole treatment, the patient died.

[The mould onychomycosis in Morocco: about 150 isolated cases in 20 years]. / Les onychomycoses à moisissure au Maroc: à propos de 150 cas isolés en 20 ans.

INTRODUCTION: the involvement of moulds in the fungal ungueal pathology is very variable. In fact a big confusion reigns because of numerous errors in the clinico-biological diagnosis, which could be responsible for therapeutic failure of onychomycosis. AIMS OF STUDY: The aim of this study was to evaluate the relative frequency of moulds involved in onychomycosis over a period of 20 years. PATIENTS AND METHODS: This is a retrospective study, conducted at the laboratory of parasitology-mycology of the Ibn Sina hospital over a period of 20 years. The patients were referred by dermatologists or general practitioners for suspected onychomycosis. The samples were studied according to good rules for performing mycological analysis. RESULTS: One hundred and fifty cases of onychomycosis were diagnosed with mould, with global prevalency of 2.78%. They mainly concern the toes (95%) with a slight female predominance (60%). The total dystrophy of the nail was the predominant clinical representation (88.3%). Moulds isolated were Aspergillus spp. in 53 cases (35.3%) and Fusarium spp. in 45 cases (30%), 19 cases (12.7%) of Scopulariopsis brevicaulis, 17 cases (11.3%) of Penicillium spp., 14 cases (9.3%) of Acremonium spp., one case of Onychocola canadensis (0.7%) and one case of Scytalidium dimitiatum (0.7%). CONCLUSION: A significant number of onychomycosis remains attributed to moulds, which highlights the contribution of the laboratory, which remains essential for the clinician to confirm the involvement of mould in onychomycosis, which allows taking into support early treatment avoiding the emergence of aesthetic complications.